| 产品详情 |
| Edit |   |
|---|
| Product Name | MST1, Recombinant, Human, GST-Tag (KRS2, YSK3, STK4) |
|---|
| Description | Purified (~70-90%). MST1 belongs to a family of proteins that share similarity with a budding yeast serine/threonine kinase, sterile-20 (Ste20). Endogenous full-length MST1 is activated by a variety of stressful stimuli, accompanied by the secondary appearance of a 36kD Thr183-phosphorylated, caspase-cleaved catalytic fragment. Recombinant MST1 undergo a robust autoactivation in vitro, mediated by an intramolecular autophosphorylation on the activation loop of an MST dimmer. MST1 can initiate apoptosis when transiently overexpressed in mammalian cells. Interference with the ability of endogenous MST1 to associate with the putative tumor suppressor proteins Nore1/RASSF can inhibit Ras-induced apoptosis. Source: Recombinant protein corresponding to human MST1 fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~83kD Biological Activity: 1120nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Accession: NM_006282 |
|---|
| Catalog # | 500283 |
|---|
| Price | |
|---|
| Order / More Info | MST1, Recombinant, Human, GST-Tag (KRS2, YSK3, STK4) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|