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| Product Name | CFL2, Recombinant, Human, aa1-166, His-Tag (Cofilin-2, Cofilin, Muscle Isoform) |
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| Description | Purity ~90% (SDS-PAGE). CFL2 belongs to the actin-binding proteins ADF family that contains 1 ADF-H domain. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Defects in CFL2 are the cause of nemaline myopathy type 7 (NEM7). Source: Recombinant corresponding to aa1-166 from human CFL2, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL Molecular Weight: ~20.9kD (MALDI-TOF) |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_068733 |
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| Catalog # | C7506-52 |
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| Order / More Info | CFL2, Recombinant, Human, aa1-166, His-Tag (Cofilin-2, Cofilin, Muscle Isoform) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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