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| Product Name | Ro/SS-A Antigen |
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| Description | Purity ~90% (SDS-PAGE). The (Ro) SS-A antigen is comprised or an acidic 60kD protein that may also be associated with a RNA ranging in size from 80 to 112 bases. The antigenic activity of the (Ro) SS-A antigen appears to be independent of the RNA since the precipitin activity remains after treatment with RNase or separation from the RNA. Anti-(Ro) SS-A autoantibodies were described originally as precipitating autoantibodies in sera of Sjogren's Syndrome and Systemic Lupus Erythematosus patients. The presence of autoantibodies against the (Ro)SS-A antigen may be used as a diagnostic aid. Elevated levels of Anti-(Ro) SS-A have been detected in as high as 96% of Sjogren's Syndrome patients, 49% of patients with Systemic Lupus Erythematosus, 83% of mothers of infants with isolated complete congenital heartblock or Neonatal Lupus Dermatitis, and over 75% of patients with Subacute Cutaneous Lupus. Recently, a strong correlation between low positive levels of Anti-(Ro) SS-A and subdinical dry |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Ro/SS-A Antigen (SSA1, Sjogren Syndrome Antigen A1, 52kD Ribonucleoprotein Autoantigen SS-A/Ro, RO52, RNF81, Tripartite Motif Protein 21, TRIM21) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | R2997-04B |
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| Price | |
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| Order / More Info | Ro/SS-A Antigen from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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