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| Product Name | Ro/SS-A Antigen (Ro-60/SS-A) |
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| Description | Purified by immunoaffinity chromatography using immobilized anti-SSA-A (Ro) immunoglobulins. Other antigens (Sm, RNP, Scl-70, Jo-1) are not detected in ELISA. Homogeneity is verified by SDS PAGE. The (Ro) SS-A antigen is comprised or an acidic 60kD protein that may also be associated with a RNA ranging in size from 80 to 112 bases (1). The antigenic activity of the (Ro) SS-A antigen appears to be independent of the RNA since the precipitin activity remains after treatment with RNase or separation from the RNA (1). Anti-(Ro) SS-A autoantibodies were described originally as precipitating autoantibodies in sera of Sjogren's Syndrome and Systemic Lupus Erythematosus patients. The presence of autoantibodies against the (Ro)SS-A antigen may be used as a diagnostic aid. Elevated levels of Anti-(Ro) SS-A have been detected in as high as 96% of Sjogren's Syndrome patients (2), 49% of patients with Systemic Lupus Erythematosus (2), 83% of mothers of infants with isolated complete congenital hear |
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| Size | 100u, 1000u |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | R2997-04 |
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| Order / More Info | Ro/SS-A Antigen (Ro-60/SS-A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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