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| Product Name | PAX8, Recombinant, Human, aa1-287, His-Tag (Paired Box Protein Pax-8 Isoform PAX8E) |
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| Description | Purity ~90% (SDS-PAGE). Paired box protein Pax-8 isoform PAX8E, also known as PAX8, is expressed in the developing and adult thyroid, the developing secretory system and at lower levels, in the adult kidney. PAX8 complexes with TTF-1 and TTF-2 to induce thyroid follicular cell differentiation and thyroid hormone biosynthesis by regulating the expression of sodium iodide symporter (NIS), thyroid peroxidase (TPO), thyroglobulin (TG) and the thyrotropin receptor (TSHR). Defects in PAX8 are the cause of congenital hypothyroidism non-goitrous type 2 (CHNG2). Source: Recombinant protein corresponding to aa1-287 from human PAX8, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~33.4kD (310aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_054698 |
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| Catalog # | 218426 |
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| Order / More Info | PAX8, Recombinant, Human, aa1-287, His-Tag (Paired Box Protein Pax-8 Isoform PAX8E) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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