| 产品详情 |
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| Product Name | Pazopanib, Free Base |
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| Description | Purity ~99%. Pazopanib is an oral, second-generation, potent and selective multi-targeted tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor and c-kit, key proteins responsible for tumor growth and angiogenesis. Pazopanib showed good potency against all of the human VEGFRs and some related tyrosine receptor kinases in vitro, and demonstrated antitumor activity against renal cell carcinoma (RCC), and breast, lung, and other related cancers. Solubility: Soluble in DMSO at 8.3mg/ml with slight warming; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-20uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. |
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| Size | 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Pazopanib, Free Base (5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamid, Armala, GW-786034) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P3113-97A |
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| Price | |
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| Order / More Info | Pazopanib, Free Base from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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