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| Product Name | Leucettine L41 ((5Z)-5-(1,3-Benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4one) |
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| Description | Purity ~98% (NMR). Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer's disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down syndrome (inhibition of DYRK1A). Neuroprotective against glutamate-induced cell death. Formula: C17H13N3O3 Solubility: DMSO or ethanol Molecular Weight: ~307.3 |
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| Size | 1mg, 5mg, 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207259 |
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| Order / More Info | Leucettine L41 ((5Z)-5-(1,3-Benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4one) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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