| 产品详情 |
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| Product Name | Cancer Hydrolase KIAA1363 Inhibitor, JW480 |
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| Description | Purity ~97% (HPLC). A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50=12nM; PC3 lysate) and murine (IC50=20nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80mg/kg/day; o.g.). Also inhibits blood carboxylesterase. Formula: C22H23NO2 Solubility: DMSO Molecular Weight: 333.4 |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cancer Hydrolase KIAA1363 Inhibitor, JW480 (2'-Isopropylphenyl-2-(2-naphthyl)ethylcarbamate, AADACL1 Inhibitor, Arylacetamide Deacetylase-Like 1 Inhibitor, NCEH1 Inhibitor, Neutral Cholesterol Ester Hydrolase 1 Inhibitor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217246 |
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| Order / More Info | Cancer Hydrolase KIAA1363 Inhibitor, JW480 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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