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| Product Name | TGFbR2, Recombinant, Human, aa190-567, GST-tag |
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| Description | Purity ≥66%. This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]. Source: Recombinant protein corresponding to aa190-567 from human transforming growth factor beta receptor 2, fused to GST-tag at N-terminal, expressed in Sf9 Insect cells. Molecular Weight: ~69.9kD Applications: Suitable for use in studying protein binding, receptor activity, and s |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TGFbR2, Recombinant, Human, aa190-567, GST-tag (TGFBR2, TGFR-2, Tranforming Growth Factor-beta Receptor II, TGFBR-II, TGF-Beta Receptor Type 2, AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2) |
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| Gene, Accession, CAS # | Accession: NM_003242, SwissProt: P37173 |
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| Catalog # | 298480 |
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| Order / More Info | TGFbR2, Recombinant, Human, aa190-567, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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