| 产品详情 |
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| Product Name | Lymphotoxin beta Receptor |
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| Description | Purified by affinity and size exclusion chromatography. Human Lymphotoxin beta receptor (LTbR, TNFSF3) is a member of the TNF receptor superfamily with similarilty to CD120a(TNFR1) and CD120b(TNFR2). It is a expressed mainly on non lymphoid tissues(1) and appears to have an important role in secondary lymphoid organ development(5). Suppression of LTbR signaling can alleviate autoimmunity(2) or exasperate mycobacterial infection(6). Its ligands include Ltab 2 and LIGHT. In mice, LTbR signaling is important for development and function of HEV(2), Dendritic cells(3), and Mast cells(4). Molecular Structure: A soluble fusion protein consisting of 10 residual amino acids from murine CD8 alpha leader sequence (KPQAPELRGS), followed by the mature extracellular (192aa) domain of human LTbR (SQPQAVP....PLEPLPP) fused to (233aa) murine IgG2a Fc (EPRGPTI....FSRTPGK). Predicted non-glycosylated molecular weight of 48.9kD. LTbR-muIg identity was confirmed by N-terminal sequencing (KPQAP) and amino acid |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Lymphotoxin beta Receptor (Human)-Murine IgG2a Fc Fusion Protein (LTBR, LT-beta-R, Tumor Necrosis Factor C Receptor, Tumor Necrosis Factor Receptor Superfamily Member 3) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L8015-03B |
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| Order / More Info | Lymphotoxin beta Receptor from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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