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| Product Name | PDGF-BB, Recombinant, Mouse |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. PDGFs are disulfide-linked dimers consisting of two 12.0-13.5kD polypeptide chains, designated PDGF-A and PDGF-B chains.The three naturally occurring PDGFs PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.The PDGFs are stored in platelet alpha-granules and are released upon platelet activation.The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development.Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms.On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB.Recombinant murine PDGF-BB is a 24.4kD disulfide-linked homodimer of two B chains (218 total amino acid |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PDGF-BB, Recombinant, Mouse (Platelet-Derived Growth Factor-BB, Glioma-derived growth factor (GDGF), Osteosarcoma-derived Growth Factor (ODGF)) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143465 |
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| Order / More Info | PDGF-BB, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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