| 产品详情 |
| Edit |   |
|---|
| Product Name | PIP5K1A, Recombinant, Human, GST-Tag (Phosphatidylinositol-4-Phosphate 5-Kinase 1 Alpha) |
|---|
| Description | Purified (~70-90%). PIP5K1A or phosphatidylinositol-4-phosphate 5-kinase 1 alpha phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1 is required for Wnt3a-induced LRP6 phosphorylation at ser1490 in mammalian cells. Wnt3a stimulates the formation of phosphatidylinositol 4,5-bisphosphates through 'frizzled' and 'dishevelled', the latter of which directly interacts with and activated PIP5KI. PIP5K1A-mediated PIP production is crucial for HIV-1 entry and the early steps of infection in permissive lymphocytes. Overexpression of wild-type PI4P5K1A increases HIV-1 Env-mediated PIP production and enhances viral replication in primary lymphocytes. Source: Recombinant protein corresponding to human PIP5K1A, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~86kD Specific Activity: 1310nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Accession: BC007833 |
|---|
| Catalog # | 500378 |
|---|
| Price | |
|---|
| Order / More Info | PIP5K1A, Recombinant, Human, GST-Tag (Phosphatidylinositol-4-Phosphate 5-Kinase 1 Alpha) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|