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| Product Name | Platelet Derived Growth Factor AA, Recombinant, Mouse |
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| Description | Purity ~98% (SDS-PAGE and HPLC). PDGFs are disulfide-linked dimers consisting of two 12-13.5kD polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet a-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-a and PDGFR-b. PDGFR-a is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-b interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-AA is a 28.7kD disulfide-linked homodimer of two A chains, 250aa. Source: Recombinant protein correspondin |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Platelet Derived Growth Factor AA, Recombinant, Mouse (PDGF-AA, Platelet-Derived Growth Factor Subunit A, PDGF Subunit A, Platelet-Derived Growth Factor A Chain, Platelet-Derived Growth Factor alpha Polypeptide, PDGF-1, PDGFA, PDGF1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149710 |
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| Order / More Info | Platelet Derived Growth Factor AA, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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