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| Product Name | Platelet Derived Growth Factor AB, Recombinant, Human |
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| Description | Purity ≥ 97% by SDS-PAGE and HPLC analyses. Endotoxin: ≤ 0.1ng/ug (1EU/ug). PDGFs are disulfide-linked dimers consisting of two 12-13.5kD polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs (PDGF-AA, PDGF-BB and PDGF-AB) are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet -granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR- and PDGFR-. PDGFR- is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR- interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AB is a 25.5kD disulfide-linked dimer, consisting of one A chain and |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Platelet Derived Growth Factor AB, Recombinant, Human (PDGF-AB, PDGF alpha, beta Polypeptide, Becaplermin, Heterodimer Platelet-derived Growth Factor, Glioblastoma-derived T-cell Suppressor Factor, BSC-1 Cell Growth Inhibitor, Polyergin, Cetermin, TGFB2, Transforming Growth Factor beta-2, SIS, c-sis) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P4258-10 |
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| Order / More Info | Platelet Derived Growth Factor AB, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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