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| Product Name | Platelet Derived Growth Factor AB, Recombinant, Human (PDGF-AB) |
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| Description | Purity ~97% (RP-HPLC, SDS-PAGE). The term `PDGF' refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets. They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family - PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist - a short form that is soluble and a long form that is retained by the extracellular matrix. Source: Recombinant protein corresponding to human PDGF-AB, a heterodimeric, non-glycosylated, polypeptide chain containing 234aa, expressed in E. coli. Molecular Weight: ~25.5kD (13.3kD alpha-chain and 12.2kD beta-chain) Biological Activity: The ED50, calculated by the dose-dependant proliferation of murine BALB/c 3T3 |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 299510 |
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| Order / More Info | Platelet Derived Growth Factor AB, Recombinant, Human (PDGF-AB) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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