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| Product Name | Midkine, Recombinant, Mouse (MK, NEGF-2) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant murine Midkine is a 13.3kD protein containing 120 amino acid residues including five intra-molecular disulfide bonds. Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml. AA Sequence: VAKKKEKVKK GSECSEWTWG PCTPSSKDCG MGFREGTCGA QTQRVHCKVP CNWKKEFGAD CKYKFESWGA CDGSTGTKAR QGTLKKARYN AQCQETIRVT KPCTSKTKSK TKAKKGKGKD Quality Control: Verified by N-terminal and Mass Spect |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143434 |
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| Order / More Info | Midkine, Recombinant, Mouse (MK, NEGF-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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