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| Product Name | TIMP1, Recombinant, Human, aa24-207, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). TIMP1 is also known as metalloproteinase inhibitor 1. The matrix metalloproteinases are inhibited by specific endogenous tissue inhibitors of metalloproteinases (TIMPs), which comprise a family of four protease inhibitors: TIMP1, TIMP2, TIMP3 and TIMP4. Overall, all MMPs are inhibited by TIMPs once they are activated but the gelatinases (MMP-2 and MMP-9) can form complexes with TIMPs when the enzymes are in the latent form. The complex of latent MMP-2 (pro-MMP-2) with TIMP-2 serves to facilitate the activation of pro-MMP-2 at the cell surface by MT1-MMP (MMP-14), a membrane-anchored MMP. The role of the pro-MMP-9/TIMP-1 complex is still unknown. Source: Recombinant protein corresponding to aa24-207 from human TIMP1, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~23kD (205aa) Applications: Suitable for use in SDS-PAGE. |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TIMP1, Recombinant, Human, aa24-207, His-Tag (Tissue Inhibitor of Metalloproteinases 1, Metalloproteinase Inhibitor 1) |
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| Gene, Accession, CAS # | Accession: NP_003245 |
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| Catalog # | 218633 |
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| Order / More Info | TIMP1, Recombinant, Human, aa24-207, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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