| 产品详情 |
| Edit |   |
|---|
| Product Name | Timp1, Recombinant, Rat, aa24-217, His-Tag (Metalloproteinase Inhibitor 1) |
|---|
| Description | Purity ~85% (SDS-PAGE). Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity. Source: Recombinant protein corresponding to aa24-217 from rat Timp1, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~25.6kD AA |
|---|
| Size | 10ug, 50ug, 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Tissue inhibitor of metalloproteinases 1, TIMP-1 |
|---|
| Gene, Accession, CAS # | SwissProt: P30120 |
|---|
| Catalog # | 375577 |
|---|
| Price | |
|---|
| Order / More Info | Timp1, Recombinant, Rat, aa24-217, His-Tag (Metalloproteinase Inhibitor 1) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|