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| Product Name | TIMP-3 (Tissue Inhibitors of Metalloproteinase 3) BioAssay™ ELISA Kit (Porcine) |
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| Description | The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD). Sample Type: Serum, cell culture supernates, saliva, plasma (heparin or EDTA). Intended Use: Sandwich High Sensitivity BioAssay™ ELISA kit for Quantitative Detection of Porcine TIMP-3. Sensitivity: <2pg/ml Range: 156pg/ml-10,000pg/ml Specificity: Recognizes natural and recombinant Porcine TIMP-3. There is no detectable cross-reactivity with other relevant proteins. Test Principle: This Porcine TIMP-3 BioAssay™ EL |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P35625 |
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| Catalog # | 396794 |
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| Order / More Info | TIMP-3 (Tissue Inhibitors of Metalloproteinase 3) BioAssay™ ELISA Kit (Porcine) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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