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| Product Name | AHCY, N-terminal GST-Tag, Recombinant, Human |
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| Description | Purified ≥90%. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. AHCY deficiency is one of the causes of hypermethioninemia, a rare disease affecting brain development and muscle strength. Down-regulation of AHCY is also associated with certain forms of cancer, Huntington's disease and Wilson's disease. Source: Recombinant corresponding to aa2-end of human AHCY with N-terminal GST tag expressed in E. coli (NM_000687). Applications: Suitable for use in enzyme kinetics, inhibitor screening and selectivity profiling. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AHCY, N-terminal GST-Tag, Recombinant, Human (Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, SAHH) |
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| Gene, Accession, CAS # | Accession: NM_000687 |
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| Catalog # | A1059-73C |
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| Order / More Info | AHCY, N-terminal GST-Tag, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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