| 产品详情 |
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| Product Name | AHCY, Recombinant, Human, aa1-432, His-Tag (Adenosylhomocysteinase Isoform 1, AdoHcyase, SAHH) |
| Description | Purity ~95% (SDS-PAGE). AHCY, also known as adenosylhomocysteinase isoform 1, is an enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AdoHcy hydrolysis is a reversible reaction with an equilibrium favoring AdoHcy formation, but hydrolysis prevails under physiological conditions due to the rapid removal of adenosine and homocysteine. Thus, AHCY's activity in mammals is directly related to homocysteine level, an independent risk factor for vascular disease. It also functions as a regulator of biological transmethylation by controlling the concentration of AdoHcy, a potent competitive inhibitor of all S- adenosyl-L-methionine methyltransferases. Source: Recombinant protein corresponding to aa1-432 from human AHCY protein, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~48.8kD (441aa) 40-57kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA |
| Size | 20ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | Accession: NP_000678 |
| Catalog # | 377694 |
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| Order / More Info | AHCY, Recombinant, Human, aa1-432, His-Tag (Adenosylhomocysteinase Isoform 1, AdoHcyase, SAHH) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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