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HNMT, Recombinant, Human, aa1-292, His-Tag (Histamine N-Methyltransferase, HMT, HNMT-S1, HNMT-S2, MRT51) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | HNMT, Recombinant, Human, aa1-292, His-Tag (Histamine N-Methyltransferase, HMT, HNMT-S1, HNMT-S2, MRT51) |
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| Description | Purity ~90% (SDS-PAGE). HNMT also known as Histamine N-methyltransferase. HNMT is found in the cytosol and uses S- adenosyl-L-methionine as the methyl donor. HNMT inactivates histamine by N-methylation. Histamine is involved in regulation and modulation of immune response through the stimulation of four distinct subtypes of receptors, H1, H2, H3, and H4, present on the target cells. Histamine is inactivated by the histamine-metabolizing enzyme histamine N-methyltransferase (HNMT) in bronchus, kidney, and the central nervous system. It plays an important role in degrading histamine and in regulating the airway response to histamine. Recombinant human HNMT, fused to His-Tag at N-terminal, expressed in E. coli and purified by using conventional chromatography. Source: Recombinant protein corresponding to aa1-292 of human HNMT, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~37.4kD (328aa), Confirmed by MALDI-TOF AA |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_008826 |
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| Catalog # | 396878 |
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| Order / More Info | HNMT, Recombinant, Human, aa1-292, His-Tag (Histamine N-Methyltransferase, HMT, HNMT-S1, HNMT-S2, MRT51) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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