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| Product Name | MIP-1a, Recombinant, Human (Macrophage Inflammatory Protein-1alpha, CCL3, LD78alpha) |
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| Description | Purity ~98% (SDS-PAGE). Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1alpha and MIP-1beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemo attractants for B cells, eosinophils and dendritic cells. Both human and mouse MIP-1alpha and MIP-1beta are active on human and mouse hematopoietic cells. Recombinant human MIP-1alpha is a 7.8kD protein containing 70aa residues, including the four highly conserved cysteine residues present in CC chemokines. Source: Recombinant protein corresponding to 7 |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CCL3, Gene ID: 6348, SwissProt: P10147 |
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| Catalog # | 220053 |
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| Order / More Info | MIP-1a, Recombinant, Human (Macrophage Inflammatory Protein-1alpha, CCL3, LD78alpha) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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