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| Product Name | PKN3, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). PKN3 or PRK3 is a serine/threonine protein kinase which can associate with RHOA in a GTP-dependent manner. PKN3 can also interact with GRAF and GRAF2 via the SH3 domains and phosphorylate these proteins. PKN3 is a mediator of malignant growth of human prostate cancer cells and functions downstream of activated PI3K. PKN3 is upregulated in human tumor cells but not in surrounding nontumorigenic tissues. Inducible knockdown of PKN3 expression inhibited metastasis in a mouse prostate tumor model. Source: Recombinant protein corresponding to human PKN3, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~130kD Specific Activity: 3nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PKN3, Recombinant, Human, GST-Tag (Serine/Threonine-protein Kinase N3, Protein Kinase PKN-beta, Protein-kinase C-related Kinase 3, PRK3) |
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| Gene, Accession, CAS # | Accession: NM_013355 |
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| Catalog # | 500400 |
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| Order / More Info | PKN3, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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