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| Product Name | IL-27, Recombinant, Human (Interleukin-27) |
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| Description | Purity ~95% (SDS-PAGE). IL-27 is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. Production in human 293 cells uses a serum-free, chemically defined media and offers authentic glycosylation. Cytokines produced in non-human expression systems may have an artificial linker, a tag, and/or not human-like posttransational modifications. Source: Recombinant protein corresponding to human IL-27, expressed in human 293 cells. Molecular Weight: ~25 and 30kD, heterodimer, glycosylated Biological Activity: ≤12ng/mL EC50, determined by the dose-dependent inhibition of HIV replication in human CD4+ T cells and in human monocyte-derived macrophages. Endotoxin: <1EU/ug |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 368995 |
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| Order / More Info | IL-27, Recombinant, Human (Interleukin-27) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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