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| Product Name | IL16, Recombinant, Human (Interleukin 16, Lymphocyte Chemoattractant Factor) |
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| Description | Purity ~95% (SDS-PAGE). Interleukin 16 (IL16) is a pleiotrophic cytokine derived from CD8+ T-cells that stimulates chemotaxis in CD4+ lymphocytes, monocytes, and eosinophils. It primes CD4+ T-cells for IL2 and IL15 responsiveness, induces T-lymphocyte Interleukin 2 (IL2) receptor expression, and inhibits HIV replication. The signalling process of IL16 is mediated by CD4, and undergoes proteolysis to yield two functional proteins. IL16 isoform 1 has the possible function of acting as a scaffolding protein to anchor ion channels in the membrane, while isoform 3 is involved in cell cycle progression in T-cells and transcriptional regulation of SKP2. IL16 mRNA expression levels have been found in various tissues such as spleen, bone marrow, thymus, and lymph nodes. Source: Recombinant protein corresponding to human IL16 expressed in E. coli. Molecular Weight: ~13.5kD Biological Activity: The ED50 is 7.5-37.5ng/mL as determined by its ability to chemoattract human CD4+ T lymphocytes (at a concentration range of 1- |
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| Size | 25ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 3603, SwissProt: Q14005 |
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| Catalog # | 500110 |
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| Order / More Info | IL16, Recombinant, Human (Interleukin 16, Lymphocyte Chemoattractant Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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