| 产品详情 |
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| Product Name | Simvastatin (MK-733, Synvinolin, BRN 4768037) |
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| Description | Purity ≥98% (HPLC). Synthetic analog of Lovastatin. Potent competitive HMG-CoA reductase inhibitor. Anti-hypercholesterolemic agent. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Inhibits the isoprenylation of Ras and Rho family GTPases. Smooth muscle cell proliferation inhibitor. Anti-adhesive, immunomodulatory and anti-inflammatory compound. Proteasome modulator. Stimulates bone formation. Apoptosis inducer. Anticancer compound. Increases cellular resistance to anticancer agents such as doxorubicin and etoposides. Suppresses ICAM-1-LFA-1 interactions, which blocks virus replication and infection. Anti-hypertensive agent. Suppresses TNF-induced NF-kappaB activation. Synonyms: MK-733; Synvinolin; BRN 4768037 |
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| Size | 10mg, 50mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MK-733, Synvinolin, BRN 4768037 |
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| Gene, Accession, CAS # | CAS: 79902-63-9 |
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| Catalog # | 45282 |
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| Order / More Info | Simvastatin (MK-733, Synvinolin, BRN 4768037) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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