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| Product Name | Vascular Endothelial Growth Factor, Recombinant, Mouse, aa27-214 |
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| Description | Purity ~95% (SDS-PAGE). Vascular endothelial growth factor (VEGF or VEGFA), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult (13). It is a member of the PDGF family that is characterized by a cystine knot structure formed by eight conserved cysteine residues (4). Alternate splicing produces isoforms including 121, 145, 165, 183, 189, and 206 amino acid (aa) forms in humans, with 120, 164 and 188aa isoforms found in mouse (1-4). Mouse VEGF188 shares 98% aa sequence identity with the appropriate isoform in rat, and 89% with human, bovine and canine VEGF. While isoforms VEGF120 and VEGF121 are freely diffusible, VEGF188, VEGF189 and VEGF206 contain the highest number of basic aa, which bind heparin and tether these isoforms to the cell surface and extracellular matrix (35). Expression of VEGF188/189 is particularly high in the embryonic lung, where it is produced by type II alveolar epithelia (6). It i |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Vascular Endothelial Growth Factor, Recombinant, Mouse, aa27-214 (VEGF 188, VAS, Vasculotropin, VEGFA, VPF) |
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| Gene, Accession, CAS # | SwissProt: Q00731 |
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| Catalog # | 145721 |
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| Order / More Info | Vascular Endothelial Growth Factor, Recombinant, Mouse, aa27-214 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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