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| Product Name | TPI1, Recombinant, Human, aa1-249, His-Tag (Triosephosphate Isomerase, TPI) |
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| Description | Purity ~90% (SDS-PAGE). TPI1 (Triosephosphate isomerase) belongs to the triosephosphate isomerase family. TPI1 catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency). TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. Source: Recombinant protein corresponding to aa1-249 from human TPI1 protein, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~28.8kD (269aa), confirmed by MALDI-TOF Endotoxin: 3000units/mg, in which one unit will convert 1umole of D-glyceraldehyde-3-phosphate to dihydroxyacetone phosphate/minute at pH 7.5 at 25 |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_000356, SwissProt: P60174 |
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| Catalog # | 377992 |
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| Order / More Info | TPI1, Recombinant, Human, aa1-249, His-Tag (Triosephosphate Isomerase, TPI) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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