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| Product Name | ARHGAP19, Recombinant, Human, aa1-494, His-SUMO-Tag (Rho GTPase-activating Protein 19) |
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| Description | Purity ~90% (SDS-PAGE). Core component of the BAF (hSWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures, termed altosomes, each composed of 2 histones octamers. Stimulates in vitro the remodeling activity of SMARCA4/BRG1/BAF190A. Involved in activation of CSF1 promoter. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BRG1-associated factor 47, BAF47Integrase interactor 1 protein, SNF5 homolog, hSNF5 |
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| Gene, Accession, CAS # | SwissProt: Q12824 |
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| Catalog # | 372326 |
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| Order / More Info | ARHGAP19, Recombinant, Human, aa1-494, His-SUMO-Tag (Rho GTPase-activating Protein 19) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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