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| Product Name | PS48 ((2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic Acid) |
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| Description | Purity ~95% (HPLC). An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (kD = 10.3uM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. It has recently been found that a combination of PS48, sodium butyrate, a histone deacetylase inhibitor and the gene Oct-4, could enhance the reprogramming efficiency of keratinocytes isolated from human skin or hair follicles over 25-fold. Molecular Weight: ~286.75 Solubility: DMSO (100mM) or EtOH (50mM) |
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| Size | 5mg, 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P9120-02 |
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| Order / More Info | PS48 ((2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic Acid) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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