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| Product Name | SOD1, Human, BioAssay™ ELISA Kit (Superoxide Dismutase Cu-Zn, Superoxide Dismutase 1, hSod1) |
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| Description | Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O -) to hydrogen peroxide, which is then catalyzed to innocuous O and H O by 222 glutathione peroxidase and catalase. Several classes of SOD have been identified. : Cu/Zn SOD (SOD1) is localized in cytosol, Mn SOD (SOD2) in mitochondria, and ecSOD (SOD3) in extracellular space. Cu/Zn SOD (SOD1) is a homodimer containing copper and zinc that is found almost exclusively in intracellular cytoplasmic spaces. The level of SOD1 elevates in response to a wide array of mechanical, chemical and biological messengers such as heat shock, shear stress, and UVB- and X-irradiation. Decreased levels of SOD1 expression can also be triggered by activation of the AP2 transcription factor. A down-regulation of SOD1 has been shown in alveolar type II epithelial cells and lung fibroblasts after exposure to hypoxia. The |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P00441 |
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| Catalog # | S8060-32P |
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| Order / More Info | SOD1, Human, BioAssay™ ELISA Kit (Superoxide Dismutase Cu-Zn, Superoxide Dismutase 1, hSod1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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