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| Product Name | TNFRSF18, Recombinant, Human, aa26-162, hIgG-His-tag |
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| Description | Purity ~95% (SDS-PAGE). TNFRSF18, also known as tumor necrosis factor receptor superfamily member 18 isoform 1, is receptor for TNFSF18. It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. TNFRSF18 mediated NF-kappa-B activation via the TRAF2/NIK pathway. Also, this protein reciprocally stimulated and activate intracellular signals regulating immune functions. In particular, GITR-driven T-cell co-stimulation was found to be the main mechanism by which the GITRL-GITR system contributes to tumor rejection and the development of autoimmune/inflammatory diseases. Source: Recombinant protein corresponding to aa26-162 from human TNFRSF18, fused to hlgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~41.6kD (376aa) 40-57KD (SDS-PAGE under reducing conditions.) AA |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNFRSF18, Recombinant, Human, aa26-162, hIgG-His-Tag (Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 1) |
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| Gene, Accession, CAS # | Accession: NP_004186 |
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| Catalog # | 369143 |
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| Order / More Info | TNFRSF18, Recombinant, Human, aa26-162, hIgG-His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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