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| Product Name | FEN-1, aa1-380, Recombinant, Human (FEN-1, Flap Structure-specific Endonuclease 1) |
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| Description | Purity ~90% (SDS-PAGE) Purified by immunoaffinity chromatography. FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Recombinant human FEN-1 protein was expressed in E. coli and purified by using conventional chromatography techniques. Recombinant protein corresponding to aa1-380 from human FEN-1 protein expressed in E. coli (NP_004102). Amino Acid sequence: MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LQQAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTAS |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_004102 |
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| Catalog # | F0048-04 |
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| Order / More Info | FEN-1, aa1-380, Recombinant, Human (FEN-1, Flap Structure-specific Endonuclease 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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