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| Product Name | LCK, Recombinant, Human, GST-Tag (Lymphocyte-specific Tyrosine Kinase, YT16, p56lck, pp58lck) |
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| Description | Purified (~70-90%). LCK (p56lck) is a member of the src family of non-receptor tyrosine kinases. It was identified as a gene rearranged and overexpressed in the murine lymphoma LSTRA, most likely as a result of the insertion of Moloney murine leukemia virus DNA immediately adjacent to the gene. Lck behaves as a proto-oncogene and can lead to cell transformation upon activation. A number of human cancer cell lines show overexpression of LCK, pointing to a possible role for this kinase in the initiation and maintenance of the transformed state in human cancers. Source: Recombinant protein corresponding to human LCK, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~84kD Specific Activity: 239nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 3932, Accession: NM_005356, SwissProt: P06239 |
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| Catalog # | 500206 |
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| Order / More Info | LCK, Recombinant, Human, GST-Tag (Lymphocyte-specific Tyrosine Kinase, YT16, p56lck, pp58lck) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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