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| Product Name | Zinc Finger E-box Binding Homeobox 1 |
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| Description | Highly Purified. C-RPQIRQKIENKPLQE, from the internal region of human ZEB1. Control peptide corresponding to polyclonal antibody, Catalog#Z0469-75A, goat x human. ZEB1 inhibits interleukin-2 (IL-2) gene expression. May be responsible for transcriptional repression of the IL-2 gene. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Defects in ZEB1 are the cause of posterior polymorphous corneal dystrophy type 3 (PPCD3) [MIM:609141]. Posterior polymorphous corneal dystrophy (PPCD) is a rare disease involving metaplasia and overgrowth of corneal endothelial cells. In patients with PPCD, these cells manifest in an epithelial morphology and gene expression pattern, produce an aberrant basement membrane, and, sometimes, spread over the iris and nearby structures in a way that increases the risk for glaucoma. Applications: Suitable for use in ELISA. Recommended Diltuinos: Optimal dilutions to be determined by the researcher. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Zinc Finger E-box Binding Homeobox 1 (ZEB1, AREB6, BZP, NIL-2A, NIL-2-A, TCF8, ZEB, ZFHEP, ZFHX1A) (Control Peptide) |
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| Gene, Accession, CAS # | Accession: NP_001121600.1; NP_110378.3 |
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| Catalog # | Z0469-75A-P |
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| Order / More Info | Zinc Finger E-box Binding Homeobox 1 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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