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| Product Name | PlGF-3, Recombinant, Human, aa19-221 (Placenta Growth Factor, PlGF, PGF) |
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| Description | Purity ~95% (SDS-PAGE). Placenta growth factor (PlGF or PGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines (1-3). Alternative splicing likely results in four human mature PlGF forms containing 131 (PlGF-1), 152 (PlGF2), 203 (PlGF-3), or 224 (PlGF-4) amino acids (aa) (1-3). The PlGF-3 form is limited to humans. PlGF-3 and PlGF-1 do not contain a heparin binding insert at the C-terminus (1, 2). Within the region shared with other PlGF isoforms (aa18-131), human PlGF-3 shares 68%, 66%, 96%, 96%, 87% and 77% aa sequence identity with mouse, rat, porcine, equine, canine and bovine PlGF, respectively. PlGF is mainly found as a variably glycosylated, secreted, 55-60kD, disulfide linked homodimer (1, 4). Mammalian cells expressing all forms of PlGF include villous trophoblasts and decidual cells, with smaller amounts in erythroblasts, keratinocytes and some endothelial cells (13, 5, 6). Circulating PlGF increases during pregnancy, rea |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P49763 |
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| Catalog # | 145719 |
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| Order / More Info | PlGF-3, Recombinant, Human, aa19-221 (Placenta Growth Factor, PlGF, PGF) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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