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| Product Name | IGF1, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). The Insulin Growth Factors belong to the Insulin gene family, the prototypic members of which include insulin and relaxin. Also known as somatomedin C, IGF1 is known to stimulate the proliferation of a wide range of cells including muscle, bone, and those of the cartilage tissue. A dominant effector of the growth hormone, mature IGF1 is generated by proteolytic removal of the N- and C-terminal pro-peptide regions. Mature human IGF1 shares 94% and 96% amino acid sequence identity with mouse and rat IGF1, respectively, while exhibiting cross-species activity. Circulating IGF1 is produced by hepatocytes while local IGF1 is produced by various other tissues in which it exerts paracrine effects. Recombinant Human IGF1 is a globular, 7.7kD protein that contains 3 native intra-molecular disulfide bonds. Source: Recombinant protein corresponding to human IGF1 expressed in E. coli. Molecular Weight: ~7.7kD Biological Activity: The ED50 as determined by a cell proliferation assay using MCF-7 cel |
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| Size | 100ug, 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IGF1, Recombinant, Human (IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IBP1, Insulin Like Growth Factor-I) |
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| Gene, Accession, CAS # | SwissProt: P01343 |
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| Catalog # | 500085 |
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| Order / More Info | IGF1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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