| 产品详情 |
| Edit |   |
|---|
| Product Name | IGF1, Recombinant, Rat (Somatomedin, Insulin-Like Growth Factor I, IGF-I, Igf1, Insulin-Like Growth Factor) |
|---|
| Description | Purity ~95% (SDS-PAGE). Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. Human IGF-I is synthesized as two precursor isoforms with N- and alternate C- terminal propeptides. These isoforms are differentially expressed by various tissues. The 7.6kD mature IGF-I is identical between isoforms and is generated by proteolytic removal of the N- and C- terminal regions. Mature human IGF-I shares 94% and 96% aa sequence identity with mouse and rat IGF-I, respectively, and exhibits cross-species activity. It shares 64% aa sequence identity with mature human IGF-II. Circulating IGF-I is produced by hepatocytes, while local IGF-I is produced by many other tissues in which it has paracrine effects. Source: Recombinant protein corresponding to rat IGF1 expressed in E. coli. Molecular Weight: ~8.0kD Biological Activity: The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤1ng/ml. Specific Activity: ≥1x1 |
|---|
| Size | 50ug, 250ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | SwissProt: P08025 |
|---|
| Catalog # | 500087 |
|---|
| Price | |
|---|
| Order / More Info | IGF1, Recombinant, Rat (Somatomedin, Insulin-Like Growth Factor I, IGF-I, Igf1, Insulin-Like Growth Factor) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|