| 产品详情 |
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| Product Name | AKR1C4, Recombinant, Human, aa1-323, GST-Tag (Aldo-keto Reductase Family 1 Member C4) |
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| Description | Purity ~90% (SDS-PAGE). Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route. Source: Recombinant protein corresponding to aa1-323 from human AKR1C4, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~64.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-alpha-HSD1 3-alpha-hydroxysteroid dehydrogenase type I Chlordecone reductase |
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| Gene, Accession, CAS # | SwissProt: P17516 |
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| Catalog # | 372206 |
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| Order / More Info | AKR1C4, Recombinant, Human, aa1-323, GST-Tag (Aldo-keto Reductase Family 1 Member C4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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