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| Product Name | MANF, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). MANF is a neurotrophic factor found mainly in central nervous tissues where it may remain localized to the endoplasmic reticulum/Golgi apparatus, or secreted. It has been shown that MANF plays an important role in protecting cells against tunicamycin and thapsigargin -induced cell death. Without MANF, cells become increasingly vulnerable to the aforementioned drugs. Also, MANF is structurally homologous to CDNF. Source: Recombinant protein corresponding to human MANF expressed in E. coli. Molecular Weight: ~18.4kD Biological Activity: The ED50 was found to be <0.5ng/ml using dose dependent proliferation of human pancreatic cells. Endotoxin: <1EU/ug (LAL) |
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| Size | 40ug, 200ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MANF, Recombinant, Human (Arginine-Rich Protein, Protein ARMET, ARP, Mesencephalic Astrocyte-Derived Neurotrophic Factor) |
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| Gene, Accession, CAS # | Gene ID: 7873, SwissProt: P55145 |
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| Catalog # | 500226 |
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| Order / More Info | MANF, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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