| 产品详情 |
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| Product Name | AKT3, active, Recombinant, Human |
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| Description | Purity ~92% (SDS-PAGE). Akt3 or Protein Kinase B g (PKB) is a serine/threonine kinase that is a member of the Akt family. In mammals, the Akt family comprises of three highly homologous members known as Akt1 (PKB), Akt2 (PKB), and Akt 3. Akt 3 like the other family members is activated in cells exposed to diverse stimuli such as hormones, growth factors, and extracellular matrix components. The activation mechanism remains to be fully characterized but occurs downstream of phosphoinositide 3-kinase (PI3K). PI3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP3), a lipid second messenger essential for the translocation of Akt family members to the plasma membrane where they are phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1) and phosphoinositide-dependent kinase-2 (PDK-2 possibly ILK). Akt 3 like the other family members phosphorylates and regulates the function of many cellular proteins involved in processes that include cellular metabolism, survival/ |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AKT3, active, Recombinant, Human (RAC-gamma Serine/Threonine-protein Kinase, RAC-PK-gamma, Protein Kinase Akt-3, Protein Kinase B gamma, PKB gamma, PKBG, STK-2) |
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| Gene, Accession, CAS # | Accession: NP_005456 |
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| Catalog # | A1125-30T |
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| Order / More Info | AKT3, active, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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