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| Product Name | β-Amyloid 1-40, Human (Control Peptide) |
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| Description | Highly purified. Control Peptide for A2275-74B (affinity purified antibody) and A2275-74L (antiserum). Human, beta Amyloid 1-40 synthetic C-terminal 7 aa synthetic peptide. Demonstrates a high degree of sequence homology with human and murine b-amyloid (1-40) and b-amyloid (1-42). Demonstrates a small amount of sequence homology with b-amyloid (1-28) and b-amyloid (12-28). No sequence homology is observed with CGRP. Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and cognition in the elderly. One of the most important and initial step involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43 aa peptides (beta amyloid1-40, 1-42, and 1-43). Polymerization of b-amyloid (Ab) and subsequent neuronal deposit (amyloid) leads to the degeneration of neurons involved in memory and cognition. Ab deposits have also been found to contain 2 additional proteins termed a-synuclein and b-synuclein. Th |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A2275-75F |
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| Order / More Info | β-Amyloid 1-40, Human (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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