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| Product Name | β-Amyloid 1-42, Human (Control Peptide) |
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| Description | Highly purified. Control Peptide for A2275-75S and A2275-75T. Human, A synthetic peptide consisting of 8aa of human beta 1-42 mapping within to the C-terminal. High degree of sequence homology with Mouse b-1-42. Demonstrates minimal sequence homology with b-1-40. Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and cognition in the elderly. One of the most important and initial step involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43 aa peptides (beta amyloid1-40, 1-42, and 1-43). Polymerization of b-amyloid (Ab) and subsequent neuronal deposit (amyloid) leads to the degeneration of neurons involved in memory and cognition. Ab deposits have also been found to contain 2 additional proteins termed a-synuclein and b-synuclein. The 140 aa a-synucleins is identical with non-Ab component (NACP) of AD. The 134 aa human b-synuclein is homologous to 14kD bovine phosphoneuroprotein 14. Mut |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A2275-74P |
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| Order / More Info | β-Amyloid 1-42, Human (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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