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| Product Name | GM2A, Recombinant, Human, aa32-193, GST-Tag (Ganglioside GM2 Activator) |
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| Description | Purity ~90% (SDS-PAGE). The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity. Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. Source: Recombinant protein corresponding to aa32-193 from human GM2A, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~44.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cerebroside sulfate activator protein, GM2-AP Sphingolipid activator protein 3, SAP-3 |
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| Gene, Accession, CAS # | SwissProt: P17900 |
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| Catalog # | 373478 |
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| Order / More Info | GM2A, Recombinant, Human, aa32-193, GST-Tag (Ganglioside GM2 Activator) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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