| 产品详情 |
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| Product Name | Carboxyl Terminal Modulator Protein, Human (CTMP) Control Peptide |
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| Description | Highly purified. A 17-aa peptide sequence near the middle region of human CTMP (1). Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase (PIK3). Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated on thr308 in the catalytic domain and ser473 in the C-terminal regulatory domain. Several protein partners for PKB have been identified. CTMP, a carboxyl terminal modulator protein, binds to PKB-a and negatively regulates PKB activity by inhibiting phosphorylation of these PKB residues. CTMP (mouse 248-aa, human 240-aa, chromosome 1q21, 22-26kD) predominantly expressed in skeletal muscle, testis, uterus, brain, and kidney, with lower levels in heart, liver, and lung. The presence of multiple transcripts suggested that CTMP undergoes alternative splicing. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C1150-02 |
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| Order / More Info | Carboxyl Terminal Modulator Protein, Human (CTMP) Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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