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| Product Name | Jagged-2, Recombinant, Human (Protein Jagged-2, hJ2, JAG2) |
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| Description | Purity ~90% (SDS-PAGE). Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-κB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development. Recombinant protein corresponding to aa1-1054 from human Jagged-2, fused at the C-terminus to the Fc portion of human IgG, expressed in HEK 293 cells. Endotoxin: ≤0.1EU/ug (LAL test, Lonza) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208530 |
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| Order / More Info | Jagged-2, Recombinant, Human (Protein Jagged-2, hJ2, JAG2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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