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| Product Name | Jagged-1, Recombinant, Mouse,Fc Human (Protein Jagged-1, CD339, JAG1) |
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| Description | Purity ≥90% (SDS-PAGE). Endotoxin: ≤0.01EUug (LAL). Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF). Biological Activity: Inhibits adipogenesis of 3T3L-1 cells Sequence: Signal peptide and extracellular domain of mouse Jagged-1 (aa1-1067) are fused at the C-terminus to the Fc portion of human IgG. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Protein Jagged-1, CD339, JAG1 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 44969 |
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| Order / More Info | Jagged-1, Recombinant, Mouse,Fc Human (Protein Jagged-1, CD339, JAG1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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