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| Product Name | FN14,Fc, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Endotoxin: ≤0.1EU/ug (LAL). TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke. Sequence: The extracellular region of human FN14 (aa28-75) is fused at the C-terminus to the Fc portion of human IgG1. Specificity: Binds to mouse and human TWEAK. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FN14,Fc, Recombinant, Human (Tumor Necrosis Factor Receptor Superfamily Member 12A, FGF-inducible 14, Tweak-receptor, CD266) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 44820 |
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| Order / More Info | FN14,Fc, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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