| 产品详情 |
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| Product Name | Syk Inhibitor V |
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| Description | Purity ~99% (HPLC). A cell-permeable, 4-thiazolyl-2-phenylaminopyrimidine compound that acts as a potent, reversible, and ATP-competitive inhibitor of spleen tyrosine kinase (Syk) (Ki=9nM). Exhibits excellent selectivity over Cdk2 (Ki=3.33uM), ROCK (Ki=2.3uM), Src (Ki=3.33uM), and ZAP70 (Ki=240nM). Shown to inhibit mast cell degranulation (IC50=70nM) that is commonly observed in asthma and other allergic diseases. Formula: C20H23N5O2S Molecular Weight: 397.5 Solubility: DMSO (50mg/ml, pale yellow solution) |
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| Size | 2mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Syk Inhibitor V ((S)-2-(2-((3,5-dimethylphenyl)amino)pyrimidin-4-yl)-N-(1-hydroxypropan-2-yl)-4-methylthiazole-5-carboxamide, Spleen Tyrosine Kinase Inhibitor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217819 |
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| Price | |
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| Order / More Info | Syk Inhibitor V from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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